Insulin and Its Metabolic Effects
Let's talk about a couple of case histories. These are actual patients that I've seen; let's start with patient A. This patient who we will just call patient A saw me one afternoon and said that he had literally just signed himself out of the hospital "AMA," or against medical advice. Like in the movies, he had ripped out his IV's.The next day he was scheduled to have his second by-pass surgery. He had been told that if he did not follow through with this by-pass surgery, within two weeks he would be dead......... To make a long story short, this gentleman right now is on no insulin. I first saw him three and a half years ago. He plays golf four or five times a week. He is on no medications whatsoever, he has no chest pain, and he has not had any surgery. He started an organization called "Heart Support of America" to educated people that there are alternatives to by-pass surgery that have nothing to do with surgery or medication.
"They have known since the fifties that if you restrict calories but maintain nutrition ...... animals can live between thirty and two-hundred percent longer."
And the common therapies for osteoporosis are drugs, and the common therapy for calaudication is surgery. For cancer reduction there is nothing. But all of these have a common cause.
The same cause as three major avenues of research in aging. One is called caloric restriction. There are thousands of studies done since the fifties on caloric restriction. They restrict calories of laboratory animals.
They have known since the fifties that if you restrict calories but maintain a high level of nutrition, called "C.R.O.N.'s:" Caloric restriction with optimal nutrition, or adequate nutrition, which would be CRAN"S, these animals can live anywhere between thirty and two-hundred percent longer depending on the species.
"Then there are Centenarian studies. ... They all have low triglycerides for their age. And they all have relatively low insulin."
Then there are Centenarian studies. There are three major centenarian studies going on around the world. They are trying to find the variable that would confer longevity among these people. Why do centenarians become centenarians? Why are they so lucky? Is it because they have low cholesterol, exercise a lot, live a healthy, clean life?Well the longest recorded known person who has ever lived, Jean Calumet of France who died last year at 122 years, smoked all of her life and drank.
What they are finding on these major centenarian studies is that there is hardly anything in common among them. They have high cholesterol and low cholesterol, some exercise and some don't, some smoke, some don't. Some are nasty as can be and some nice and calm and nice. Some are ornery, but they all low sugar, relatively for their age. They all have low triglycerides for their age.
And they all have relatively low insulin. Insulin is the common denominator in everything I've just talked about. They way to treat cardiovascular disease and the way I treated my stepfather, the way I treated the high risk cancer patient, and osteoporosis, high blood pressure, the way to treat virtually all the so-called chronic diseases of aging is to treat insulin itself.
"We know now that aging is a disease ..... all the so-called chronic diseases of aging are symptoms."
Insulin resistance is the basis of all of the chronic diseases of aging, because the disease itself is actually aging.We know now that aging is a disease. The other case studies that I mentioned, cardiovascular disease, osteoporosis, obesity, diabetes, cancer, all the so-called chronic diseases of aging, auto-immune diseases, those are symptoms....... Now, the medical profession is continuously segregating more and more symptoms into diseases, they call the symptoms diseases. .... It is the same thing with cholesterol.
If you have high cholesterol it is called hypercholesterolemia. Hypercholesterolemia has become the code for the disease when it is only the symptom. So they treat that symptom and what are they doing to the heart? Messing it up.
"We've known for many years that sugar depresses the immune system. ... It doesn't matter what disease you are talking about - insulin is going to have its hand in it, if not totally controlling it. "
We've known for many years that sugar depresses the immune system. We have known that for decades. .... A blood sugar value of 120 reduces the phagocytic index seventy-five percent.Here we are getting a little bit further down into the roots of disease. It doesn't matter what disease you are talking about, whether you are talking about a common cold or about cardiovascular disease, or osteoporosis or cancer, the root is always going to be at the molecular and cellular level, and I will tell you that insulin is going to have its hand in it, if not totally controlling it
What is the purpose of insulin in humans? If you ask your doctor, they will say that it's to lower blood sugar and I will tell you right now, that is a trivial side effect. Insulin's evolutionary purpose, among others at least known right now, we are looking at others, is to store excess nutrients.
heart attacks are two to three times more likely to happen after a high carbohydrate meal."
insulin also causes the retention of sodium, which causes the retention of fluid, which causes high blood pressure and fluid retention: congestive heart failure...... What does all of this do to the heart? Not very good things. There was a study done a couple of years ago, a good, down to earth nicely conducted study that showed that heart attacks are two to three times more likely to happen after a high carbohydrate meal. They said specifically NOT after a high fat meal.Why is that? Because the immediate effects of raising your blood sugar from a high carbohydrate meal is to raise insulin and that immediately triggers the sympathetic nervous system which will cause arterial spasm, constriction of the arteries. If you take anybody prone to a heart attack and that is when they are going to get it.
"So the way we age is that we turn rancid and we caramelize. It's very true."
You can slow the rate of aging. Not just even the rate of disease, but the actual rate of aging itself can be modulated by insulin. .... there is some pretty good evidence that even in humans we still retain the capacity to control lifespan at least partially. We should be living to be 130, 140 years old routinely.If you have a carbohydrate that is not a fiber it is going to be turned into a sugar, whether it be glucose or not. It may be fructose ... , fructose is worse for you then glucose, so if you just go by blood sugar .... it doesn't mean that you are not raising your blood fructose...... Glucose combines with anything else really, it's a very sticky molecule. ....Just take sugar on your fingers. It's very sticky. It sticks specifically to proteins. ..... the term for glycation in the food industry is carmelization. They use it all the time, that is how you make caramel. So the way we age is that we turn rancid and we caramelize. It's very true. And that is what gets most of us. If that doesn't get us, then the genetic causes of aging will, because every cell in your body has genetic programs to commit suicide.
"Your primary energy source ideally would come mostly from mono-unsaturated fat."
general, over 50% of the calories should come from fat, but not from saturated fat. ..... Saturated fat is a hard fat. We can get the fats from foods to come mostly from nuts. Nuts are a great food because it is mostly mono-unsaturated. Your primary energy source ideally would come mostly from mono-unsaturated fat. It's a good compromise. It is not an essential fat, but it is a more fluid fat. Your body can utilize it very well as an energy source.
"I would go 20% of calories from carbs, 25 to 30% of calories from protein, and 60-65% from fat."
I would go 20% of calories from carbs. Depending on the size of the person, 25 to 30% of calories from protein, and 60-65% from fat. You can get non-grain fed beef.Insulin is not the only cause of disease. There are other considerations such as iron. We know that high iron levels are bad for you. If a person's ferritin is high, red meat is out for a while, till we get their iron down. SO there are other things involved about if we are going to allow a person to eat red meat or not.There is a great deal of difference between a non-grain fed cow and a grain fed cow. Non-grain fed will have only 10% or less saturated fat. Grain fed can have over 50%.
"There is a big difference. A non-grain fed cow will actually be high in Omega 3 oils."
There is a big difference. A non-grain fed cow will actually be high in Omega 3 oils. Plants have a pretty high percentage of Omega 3, and if you accumulate it by eating it all day, every day for most of your life, your fat gets a pretty high proportion of Omega 3. I would try for 50% oleic fat, and the others would depend on the individual, but about 25% of the other two...... I like sardines if they will eat them. Sardines are a very good therapeutic food. They are baby fish so they haven't had time to accumulate a bunch of metal. They are smoked so they are not cooked and the oil is not spoiled in them. You have to eat the whole thing. Not the boneless and skinless. You need to eat all the organs and they are high in vitamins and magnesium.
"Insulin is by far your biggest poison."
So if people are worried about chromosomal damage from chromium, what they should really be worried about instead is high blood sugar. Insulin is by far your biggest poison...... The lowering of insulin is going to be better than any possible detriment of any of the therapies you are using. Insulin is associated with cancer, everything.